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COMPANY RESEARCH

20n Bio

A cyclic peptide discovery company using trillion-scale peptide libraries, screening, and chemical optimization for internal programs and partnerships. Its website identifies oral peptide therapeutics as one potential application.

Company at a glance

Corporate information

Company entity
20n Bio
Headquarters / principal office
Great Philadelphia, PASelf-reported location on the company LinkedIn page; regional scope may differ from the legal or global headquarters. ↗
Founded
2021 ↗ ↗ ↗
Ownership / capital status
PrivatePrivately held; venture-backed ↗ ↗ ↗
Official corporate reference
https://www.20n.bio/ ↗
LinkedIn company page
LinkedIn ↗ ↗
Latest financing / award identified
2026-05-20 · Seed+ · $7,500,000 ↗ ↗ ↗

The issuer announced a $7.5 million Seed+ round without naming the strategic lead or London investor. BlueRun’s role in2021 should not be transferred to the2026 round.

Profile review: 2026-11-04 · Fields retain their individual source dates. Undisclosed values are not zero; early or historical events do not establish the latest financing. Awards and acquisitions are distinguished from equity rounds.

Disease tags match recorded text mentions and require program-level verification.

Technology, programs & evidence

A cyclic peptide discovery company using trillion-scale peptide libraries, screening, and chemical optimization for internal programs and partnerships. Its website identifies oral peptide therapeutics as one potential application.

Program / serviceTarget / indicationRepresentative stageEvidence & scope
Cyclic peptide discovery and partnering platformNot disclosed · Not disclosed未披露No human oral results confirmed

Related news & literature

Company-name matches are discovery leads; verify entity identity and transaction roles in the original source.

20n Bio / BioSpace

Discovery-platform reference: 20n Bio raises $7.5 million in Seed+ financing

20n Bio announced $7.5 million in Seed+ financing to advance AI-enabled cyclic peptide discovery, screening workflows, and its therapeutic pipeline. The company identifies oral peptides among potential applications but has not disclosed a validated clinical oral cyclic peptide candidate or human oral pharmacokinetics. The strategic lead investor was unnamed; investors from earlier rounds should not be assigned to this financing.

Same-field reading (not company-specific)
Johnson & Johnson (PR Newswire)

Icotrokinra meets Phase 3 joint-response endpoint in biologic-naive psoriatic arthritis

Johnson & Johnson reported that 58% of patients receiving icotrokinra 200 mg achieved ACR20 at Week 16 in ICONIC-PsA 1, versus 41% with placebo. The oral IL-23 receptor peptide also showed skin responses. The company reported no new safety signals through Week 24; active psoriatic arthritis remains an investigational indication.

Entera Bio investor filing

Adjacent oral-peptide field: Entera reports $265.9 million cash as EB613 Phase 3 preparations continue

Entera reported $265.9 million in cash and cash equivalents at September 30, plus $6.5 million in restricted cash. Its November 6 update targets first site activation for an approximately 900-patient EB613 osteoporosis Phase 3 trial in late 2026. EB613 is an oral PTH(1-34) program, included here as an adjacent oral-peptide delivery development, not a cyclic-peptide candidate.

Johnson & Johnson

ICONIC-ASCEND reports icotrokinra noninferiority to ustekinumab in plaque psoriasis

Johnson & Johnson reported that ICONIC-ASCEND met its Week 16 co-primary endpoints: PASI 90 responses were 55.2% with icotrokinra versus 3.6% with placebo, and IGA 0/1 responses were 70.4% versus 9.5%. At Week 28, the oral peptide met noninferiority criteria versus ustekinumab across multiplicity-controlled key secondary skin-clearance endpoints.

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Sources & open questions

  • Included as a discovery ecosystem company, without a confirmed clinical oral cyclic peptide candidate.
  1. 20n Bio official company and platform overview ↗原始公司或监管来源 · Not Stated
  2. 2021issuer founding and seedrelease ↗20nbio · 2021-12-17
  3. 2026issuer Seed+ release distributedviaBioSpace ↗20nbio · 2026-05-20
  4. Company-managed LinkedIn profile — self-reported location ↗20n Bio · Checked 2026-11-04; source publication date retained where stated

Inclusion is not endorsement or partner qualification. Assess company claims, clinical evidence, and project-specific capabilities separately.

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