COMPANY RESEARCHOffers drug product formulation development and manufacturing for small molecules, TIDES, and bioconjugates. Its U.S. business discloses early oral formulation development and GMP supply.
Profile review: 2026-11-04 · Fields retain their individual source dates. Undisclosed values are not zero; early or historical events do not establish the latest financing. Awards and acquisitions are distinguished from equity rounds.
Amounts retain their original currency and units. Consolidated group revenue is not standalone CRO/CDMO service revenue. Year-to-date periods are not standalone quarters.
| Period | Currency / basis | Revenue | Net profit | Operating cash flow | Report |
|---|---|---|---|---|---|
| FY2025 2025-12-31 | CNY PRC Accounting Standards / consolidated | 3,419,829,520.97 | 96,339,888.88 Net income attributable to shareholders of the listed company | 757,012,818.8 | Original ↗ |
| 2026Q3 (YTD) 2026-09-30 | CNY PRC Accounting Standards / consolidated | 2,764,694,178.84 | -112,147,784.74 Net income attributable to shareholders of the listed company | 460,193,708.59 | Original ↗ |
Disease tags match recorded text mentions and require program-level verification.
The TIDES platform covers process development, analytics, and manufacturing for monocyclic, polycyclic, and modified peptides. This review did not confirm a named oral cyclic peptide program.
Offers drug product formulation development and manufacturing for small molecules, TIDES, and bioconjugates. Its U.S. business discloses early oral formulation development and GMP supply.
Provides CDMO services for small-molecule APIs and drug products, cell and gene therapies, peptides, oligonucleotides, and conjugates.
Listed as SZSE 300363; original 2025 annual and 2026Q3 (YTD) reports reviewed.
| Program / service | Target / indication | Representative stage | Evidence & scope |
|---|---|---|---|
| Monocyclic / polycyclic peptide CDMO services | Not disclosed · Not disclosed | 未披露 | Quantitative human results not confirmed in this review |
| Formulation development / contract manufacturing capabilities | Defined by the client project · Defined by the client project | Services / platform | Service pages do not establish human evidence for every project |
| Multimodality CDMO platform | Not applicable (services/platform) · Drug research and manufacturing services for clients | Services / platform | Not applicable: service capabilities are not clinical drug candidates; E4 does not rate service quality. |
Company-name matches are discovery leads; verify entity identity and transaction roles in the original source.
Porton Pharma Solutions reported consolidated revenue of RMB2.765 billion, up 8.66%, and an attributable net loss of RMB112.1 million for the nine months ended September 30, 2026. The group posted an attributable loss of RMB112.1 million; impairment related to its discontinued Slovenia project affected earnings. The quarterly filing is unaudited and covers the year-to-date period.
Johnson & Johnson reported that 58% of patients receiving icotrokinra 200 mg achieved ACR20 at Week 16 in ICONIC-PsA 1, versus 41% with placebo. The oral IL-23 receptor peptide also showed skin responses. The company reported no new safety signals through Week 24; active psoriatic arthritis remains an investigational indication.
Entera reported $265.9 million in cash and cash equivalents at September 30, plus $6.5 million in restricted cash. Its November 6 update targets first site activation for an approximately 900-patient EB613 osteoporosis Phase 3 trial in late 2026. EB613 is an oral PTH(1-34) program, included here as an adjacent oral-peptide delivery development, not a cyclic-peptide candidate.
Johnson & Johnson reported that ICONIC-ASCEND met its Week 16 co-primary endpoints: PASI 90 responses were 55.2% with icotrokinra versus 3.6% with placebo, and IGA 0/1 responses were 70.4% versus 9.5%. At Week 28, the oral peptide met noninferiority criteria versus ustekinumab across multiplicity-controlled key secondary skin-clearance endpoints.
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