MicroED in natural product and small molecule research
Academic source · Natural Product Reports
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Site published: 2026-11-03 · Updated: 2026-11-03
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What the paper reports
Covering work from 2013 through 2020, this highlight reviews how MicroED expanded from protein crystallography into natural products and small organic molecules. It discusses examples obtained from extremely small crystals and outlines progress in specimen handling, data collection, and structural analysis. The article offers historical context and practical possibilities, not a prospective pharmaceutical success-rate benchmark.
Why this paper is included
The review connects natural-product stereochemistry and small-molecule crystallography, providing context for discovery teams considering MicroED alongside established analytical methods.
The interpretation above is analysis, not a conclusion attributed to the original source.
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