The Elusive Structure of Levocetirizine Dihydrochloride Determined by Electron Diffraction
Academic source · Angewandte Chemie International Edition
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Site published: 2026-11-03 · Updated: 2026-11-03
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What the paper reports
The crystal structure of levocetirizine dihydrochloride was determined by 3D ED/MicroED from crystalline powder extracted from commercially available tablets. Dynamical refinement also supported its absolute configuration. The study provides an example of identifying and characterizing an API within a microcrystalline mixture, without requiring the growth of large single crystals or implying that every formulated product is equally accessible.
Why this paper is included
A prominent formulated-product example that links API identification, molecular structure, and absolute configuration within one diffraction investigation.
The interpretation above is analysis, not a conclusion attributed to the original source.
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