The Crystal Structure of Orthocetamol Solved by 3D Electron Diffraction
Academic source · Angewandte Chemie International Edition
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Site published: 2026-11-03 · Updated: 2026-11-03
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What the paper reports
Researchers solved the previously unknown crystal structure of orthocetamol, a pharmaceutical compound that had not yielded single crystals suitable for X-ray diffraction. The approach combined low-dose three-dimensional electron-diffraction acquisition with a single-electron detector. The case illustrates structure determination from challenging small crystals rather than requiring successful growth of larger specimens first.
Why this paper is included
A concrete example of resolving a long-standing pharmaceutical crystal-structure gap, useful when evaluating where electron diffraction adds practical value.
The interpretation above is analysis, not a conclusion attributed to the original source.
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