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COMPANY RESEARCH

Jing Medicine Technology

The official pipeline explicitly lists HJ-002 and HJ-004 as EGFR PROTACs for NSCLC and advanced cancers, respectively.

Company at a glance

Corporate information

Company entity
和径医药科技(上海)有限公司/Jing Medicine
Headquarters / principal office
Shanghai, ChinaOffice location disclosed on the corporate website; a sole legal or global headquarters is not inferred. ↗
Founded
2017 ↗
Ownership / capital status
PrivateSeries B (database record; original announcement not verified) ↗
Official corporate reference
https://www.jingmedicine.com/ ↗
Latest financing / award identified
2021-03 · Series B (database record) · Not disclosed ↗
LinkedIn company page
Independent company page not verified

The database lists Zhangjiang Torch Venture Capital. The company website confirms investors but does not specify the round.

Profile review: 2026-11-04 · Fields retain their individual source dates. Undisclosed values are not zero; early or historical events do not establish the latest financing. Awards and acquisitions are distinguished from equity rounds.

Disease tags match recorded text mentions and require program-level verification.

Technology, programs & evidence

The official pipeline explicitly lists HJ-002 and HJ-004 as EGFR PROTACs for NSCLC and advanced cancers, respectively.

Program / serviceTarget / indicationRepresentative stageEvidence & scope
HJ-002EGFR · See individual trial / indication; not individually confirmed in this reviewStage not disclosedHuman results not confirmed in this review
HJ-004EGFR · See individual trial / indication; not individually confirmed in this reviewStage not disclosedHuman results not confirmed in this review

Related news & literature

Company-name matches are discovery leads; verify entity identity and transaction roles in the original source.

No cataloged update explicitly mentions this company.

Same-field reading (not company-specific)
Nature Materials

In situ CAR engineering and nanoparticle-mediated TREM2 degradation for macrophage reprogramming in malignant ascites

A Nature Materials study describes mRNA-loaded LNPs that reprogram tumor-associated macrophages into Claudin18.2-targeting CAR macrophages. The lipid formulation also promotes TREM2 internalization and degradation, reshaping immune responses. The original abstract reports tumor suppression and longer survival with PD-1 blockade in mice, plus ex vivo patient-sample findings. These findings do not demonstrate clinical efficacy in treated patients.

Frontiers in Pharmacology

Review assesses the safety limits and translational gaps of MCL-1 degradation strategies

A Frontiers in Pharmacology review compares direct MCL-1 inhibition with approaches that reduce its abundance, including transcriptional interventions and targeted degradation. The original abstract highlights limited single-agent activity and cardiac safety concerns with inhibitors, while positioning degradation as an unvalidated clinical strategy. Biomarker-guided combinations and dynamic BH3 profiling are discussed; this review does not report a new clinical trial.

C4 Therapeutics (GlobeNewswire)

C4 completes first cemsidomide–elranatamab safety-cohort enrollment and updates Phase 2 timeline

C4 Therapeutics reported completed enrollment of the first safety cohort in its Phase 1b cemsidomide–elranatamab combination trial. It expects Phase 2 MOMENTUM enrollment to finish in the first quarter of 2027, with initial response-rate data in the second half. At September 30, cash, cash equivalents and marketable securities totaled $274.7 million, with projected runway through 2028.

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Sources & open questions

  • Pipeline stages are presented graphically and could not be reliably parsed from text in this review. Administration routes and human results were not confirmed.
  1. Product pipeline ↗Jing Medicine Technology · Undated · 2026-10-31accessed
  2. 关于和径 ↗和径医药 · Undated · 2026-10-31accessed
  3. 和径医药项目及融资历史 ↗36氪 · Not stated
  4. 和径医药完成约1亿元A轮融资 ↗动脉网 · 2017-12-01
  5. Jing Medicine Technology — official page checked November 4, 2026 ↗Jing Medicine Technology · 2026-11-04 retrieval; original page date retained where shown

Inclusion is not endorsement or partner qualification. Assess company claims, clinical evidence, and project-specific capabilities separately.

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