Mass-spectrometry-based proteomics: from single cells to clinical applications
Academic source · Nature
Source published: · Event / reporting date: 2025-02-26
Site published: 2026-11-04 · Updated: 2026-11-04
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What the paper reports
This review surveys improvements in proteomics sample preparation, instrumentation, data acquisition, and analysis. It connects single-cell and spatial profiling with protein interactions, modifications, and biomarker discovery in body fluids. Clinical implementation is discussed as an opportunity with remaining challenges, rather than proof that every discovery assay is ready for diagnostic use.
Why this paper is included
A broad starting point for biomarker discovery and the distinction between research workflows and clinical implementation.
The interpretation above is analysis, not a conclusion attributed to the original source.
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